ZFIN ID: ZDB-GENE-030131-298
Gene Name: CDC-like kinase 2a
Gene Symbol: clk2a    Nomenclature History

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Previous Names: fb20c02, si:ch211-81a5.7, wu:fb20c02 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and protein kinase activity. Predicted to be involved in protein phosphorylation. Orthologous to human CLK2 (CDC like kinase 2).
Genome Resources: Alliance (1),  Gene:558981 (1),  Ensembl(GRCz11):ENSDARG00000062954 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36783 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45660 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH clk2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH clk2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein phosphorylation (more)
    Molecular Function ATP binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000719 Protein kinase domain
    Active_site IPR008271 Serine/threonine-protein kinase, active site
    Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
    Binding_site IPR017441 Protein kinase, ATP binding site
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript clk2a-205 (1)    Ensembl 2192
    mRNA clk2a-201 (1)    Ensembl 2292
    clk2a-202 (1)    Ensembl 2336
    ncRNA clk2a-004 (1)    Ensembl 597
    clk2a-005 (1)    Ensembl 835
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM clk2a No data available
    MARKER RELATIONSHIPS
    clk2a Contained in: [BAC] CH211-81A5 (1)
    clk2a Encodes: [EST] fb20c02
    [cDNA] MGC:198297 (1), MGC:198299 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044879 (1) 2336 bp
    Genomic GenBank:CR626935 (1) 166134 bp
    Select Tool
    Polypeptide UniProtKB:Q1L8U5 (1) 527 aa
    Sequence Information (all 32)
    ORTHOLOGY for clk2a ( Chr: 19 )
    CITATIONS (18)