Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-29
Gene Name: arrestin, beta 2a
Gene Symbol: arrb2a
Previous Names: ARRB2b1 (1), fc14e09, hm:zeh0294, wu:fc14e09, zeh0294, zgc:66353
Location: Chr: 10   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [MGC:66353]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
  presumptive segmental plate, somite, somite anterior region, tail bud (all 5) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la010193Tg, sa21727
Knockdown reagents: MO1-arrb2a (1), MO2-arrb2a (1)
PHENOTYPE
Data: Fig. 4 from Mahabaleshwar et al., 2012
Observed in: germ cell migration, primordial germ cell
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of chemokine activity (more)
Cellular Component cellular_component (more)
Molecular Function molecular_function (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000698 (1)
  • InterPro:IPR011021 (1)
  • InterPro:IPR011022 (1)
  • InterPro:IPR014752 (1)
  • InterPro:IPR014753 (1)
  • InterPro:IPR014756 (1)
  • InterPro:IPR017864 (1)
  • PROSITE:PS00295 (1)
  • Pfam:PF00339 (1)
  • Pfam:PF02752 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA arrb2a-001 (1) 2008
    ncRNA arrb2a-002 (1) 846
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM arrb2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    arrb2a Contained in: [Fosmid] CH1073-143L10 (1) (order this)
    arrb2a Encodes: [EST] fc14e09
    [cDNA] MGC:66353 (1) (order this), MGC:192878 (1) (order this)
    arrb2a Has Artifact: [EST] zeh0294
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_214681 (1) 1988 bp
    Genomic GenBank:CU469521 (1) 31929 bp
    Select Tool
    Polypeptide UniProtKB:E7F428 (1) 414 aa
    Sequence Clusters UniGene:4114 (1)
    Sequence Information (all 22)
    OTHER arrb2a GENE PAGES
  • Gene:321378 (1)
  • VEGA:OTTDARG00000031025 (1)
  • Ensembl(Zv9):ENSDARG00000039215 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish arrb2a 10  
    Human ARRB2 17 (17p13)
  • OMIM:107941
  • Gene:409
  • Mouse Arrb2 11 ( 42.99 cM)
  • MGI:99474
  • Gene:216869
  • Orthology Details
    CITATIONS (24)