ZFIN ID: ZDB-GENE-030131-29
Gene Name: arrestin, beta 2a
Gene Symbol: arrb2a

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Previous Names: ARRB2b1 (1), fc14e09, hm:zeh0294, wu:fc14e09, zeh0294, zgc:66353

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Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [MGC:66353]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
  presumptive segmental plate, somite, somite anterior region, tail bud (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010193Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21727 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-arrb2a (1), MO2-arrb2a (1)
    PHENOTYPE
    Data: Fig. 4 from Mahabaleshwar et al., 2012
    Observed in: germ cell migration, primordial germ cell
    DISEASE ASSOCIATED WITH arrb2a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of chemokine activity (more)
    Cellular Component cellular_component (more)
    Molecular Function molecular_function (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000698 (1)
  • InterPro:IPR011021 (1)
  • InterPro:IPR011022 (1)
  • InterPro:IPR014752 (1)
  • InterPro:IPR014753 (1)
  • InterPro:IPR014756 (1)
  • InterPro:IPR017864 (1)
  • PROSITE:PS00295 (1)
  • Pfam:PF00339 (1)
  • Pfam:PF02752 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA arrb2a-001 (1) 2008
    ncRNA arrb2a-002 (1) 846
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM arrb2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    arrb2aContained in: [Fosmid] CH1073-143L10 (1) (order this)
    arrb2aEncodes: [EST] fc14e09
    [cDNA] MGC:66353 (1) (order this), MGC:192878 (1) (order this)
    arrb2aHas Artifact: [EST] zeh0294
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_214681 (1) 1988bp
    Genomic GenBank:CU469521 (1) 31929bp
    Select Tool
    Polypeptide UniProtKB:F1QLG1 (1) 406aa
    Sequence Clusters UniGene:4114 (1)
    Sequence Information (all 17)
    OTHER arrb2a GENE PAGES
  • Gene:321378 (1)
  • VEGA:OTTDARG00000031025 (1)
  • Ensembl(GRCz10):ENSDARG00000039215 (1)
  • ORTHOLOGY for arrb2a (Chr: 10)
    Species Symbol Chromosome Accession # Evidence
    Human ARRB2 17
  • Gene:409
  • OMIM:107941
  • HGNC:712
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (2)
    Mouse Arrb2 11
  • MGI:99474
  • Gene:216869
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (25)