ZFIN ID: ZDB-GENE-030131-29
Gene Name: arrestin, beta 2a
Gene Symbol: arrb2a    Nomenclature History

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Previous Names: ARRB2b1 (1), fc14e09, hm:zeh0294, wu:fc14e09, zeh0294, zgc:66353

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have angiotensin receptor binding activity. Involved in regulation of chemokine activity and regulation of receptor recycling. Predicted to localize to cytoplasm. Is expressed in presumptive segmental plate; somite; and tail bud. Orthologous to human ARRB2 (arrestin beta 2).
Genome Resources: Alliance (1),  Gene:321378 (1),  Ensembl(GRCz11):ENSDARG00000039215 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [MGC:66353]
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010193Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21727 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arrb2a N/A 1
    MO2-arrb2a N/A 1
    DISEASE ASSOCIATED WITH arrb2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arrb2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of chemokine activity (more)
    Cellular Component cytoplasm (more)
    Molecular Function angiotensin receptor binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arrb2a-201 (1)    Ensembl 2008
    ncRNA arrb2a-002 (1) 846
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arrb2a No data available
    MARKER RELATIONSHIPS
    arrb2a Contained in: [Fosmid] CH1073-143L10 (1)
    arrb2a Encodes: [EST] fc14e09
    [cDNA] MGC:66353 (1), MGC:192878 (1)
    arrb2a Has Artifact: [EST] zeh0294
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_214681 (1) 1988 nt
    Genomic GenBank:CU469521 (1) 31929 nt
    Select Tool
    Polypeptide UniProtKB:A0A286YBG8 (1) 414 aa
    Sequence Information (all 18)
    ORTHOLOGY for arrb2a ( Chr: 10 )
    CITATIONS (32)