Gene

dyrk2

ID
ZDB-GENE-030131-2804
Name
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Symbol
dyrk2 Nomenclature History
Previous Names
  • fc18c09
  • si:ch211-266a5.8
  • wu:fa09g03
  • wu:fc18c09
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Predicted to localize to cytoplasm; cytoskeleton; and nucleus. Is expressed in central nervous system; myotome; and spinal cord. Orthologous to human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tanaka et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dyrk2 Human Ortholog
No data available
Associated With dyrk2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR042521 Dual specificity tyrosine-phosphorylation-regulated kinase
Domain Details Per Protein
Protein Length Dual specificity tyrosine-phosphorylation-regulated kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A0A2R8QCS7 577
UniProtKB:A0A0R4ITS5 598
UniProtKB:Q5RHV3 587
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations