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ZIRC
ZFIN ID: ZDB-GENE-030131-2804
Gene Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Gene Symbol: dyrk2    Nomenclature History

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Previous Names: fc18c09, si:ch211-266a5.8, wu:fa09g03, wu:fc18c09

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Predicted to localize to the cytoplasm; cytoskeleton; and nucleus. Is expressed in central nervous system; myotome; and spinal cord. Orthologous to human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2).
Genome Resources: Alliance (1),  Gene:557602 (1),  Ensembl(GRCz11):ENSDARG00000094646 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30608 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dyrk2 N/A 2
    DISEASE ASSOCIATED WITH dyrk2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dyrk2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dyrk2-202 (1)    Ensembl 5073
    ncRNA dyrk2-002 (1)    Ensembl 4704
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dyrk2 No data available
    MARKER RELATIONSHIPS
    dyrk2 Contained in: [BAC] CH211-266A5 (1) (order this)
    dyrk2 Encodes: [EST] fa09g03 (1), fc18c09
    [cDNA] MGC:162783 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044833 (1) 2916 bp
    Genomic GenBank:BX465210 (1) 171708 bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4ITS5 (1) 598 aa
    Sequence Clusters UniGene:150575 (1)
    Sequence Information (all 22)
    ORTHOLOGY for dyrk2 ( Chr: 4 )
    CITATIONS (27)