Gene

bcar1

ID
ZDB-GENE-030131-2774
Name
BCAR1 scaffold protein, Cas family member
Symbol
bcar1 Nomenclature History
Previous Names
  • fc17f11
  • wu:fc17f11 (1)
  • zgc:175192
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to be involved in actin filament reorganization; cell migration; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in breast ductal carcinoma. Orthologous to human BCAR1 (BCAR1 scaffold protein, Cas family member).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from O'Hare et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bcar1 Human Ortholog
No data available
Associated With bcar1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR014928 Serine rich protein interaction domain
Domain IPR021901 CAS family, C-terminal
Domain IPR035745 BCAR1, SH3 domain
Family IPR028848 Breast cancer anti-estrogen resistance protein 1
Family IPR037362 CAS family
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR038319 CAS, serine rich four helix bundle domain superfamily
Domain Details Per Protein
Protein Length BCAR1, SH3 domain Breast cancer anti-estrogen resistance protein 1 CAS family CAS family, C-terminal CAS, serine rich four helix bundle domain superfamily Serine rich protein interaction domain SH3 domain SH3-like domain superfamily
UniProtKB:A0A2R8QGB6 934
UniProtKB:A0A286YA76 961
UniProtKB:B5DE36 919
UniProtKB:A0A2R8QJQ5 919
UniProtKB:A0A2R8Q9D0 946
UniProtKB:A0A2R8QFW9 890
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations