ZFIN ID: ZDB-GENE-030131-2774
Gene Name: BCAR1 scaffold protein, Cas family member
Gene Symbol: bcar1    Nomenclature History

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Previous Names: fc17f11, wu:fc17f11 (1), zgc:175192

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to be involved in actin filament reorganization; cell migration; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in breast ductal carcinoma. Orthologous to human BCAR1 (BCAR1 scaffold protein, Cas family member).
Genome Resources: Alliance (1),  Gene:568309 (1),  Ensembl(GRCz11):ENSDARG00000056525 (2)
GENE EXPRESSION
All Expression Data: Fig. S1 from O'Hare et al., 2016
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027931Tg Transgenic Insertion Unknown Unknown DNA
sa391 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1865 Point Mutation Unknown Premature Stop ENU
    sa9019 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11159 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11775 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36652 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa39201 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-bcar1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH bcar1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bcar1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bcar1-201 (1)    Ensembl 5304
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bcar1 No data available
    MARKER RELATIONSHIPS
    bcar1 Contained in: [BAC] DKEY-11D18 (1) (order this)
    bcar1 Encodes: [EST] fc17f11, wz10005
    [cDNA] MGC:175192 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001135133 (1) 5349 nt
    Genomic GenBank:CR933017 (1) 197925 nt
    Select Tool
    Polypeptide UniProtKB:A0A286YA76 (1) 961 aa
    Sequence Information (all 22)
    ORTHOLOGY for bcar1 ( Chr: 18 )
    CITATIONS (25)