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ZIRC
ZFIN ID: ZDB-GENE-030131-2725
Gene Name: DnaJ heat shock protein family (Hsp40) member B12a
Gene Symbol: dnajb12a    Nomenclature History

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Previous Names: dnajb12, wu:fc16f06, wu:fi38b10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein; chaperone cofactor-dependent protein refolding; and ubiquitin-dependent ERAD pathway. Predicted to localize to the endoplasmic reticulum membrane. Orthologous to human DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12).
Genome Resources: Alliance (1),  Gene:324005 (1),  Ensembl(GRCz11):ENSDARG00000039363 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63739]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018534Tg Transgenic Insertion Unknown Unknown DNA
sa6308 Point Mutation Unknown Premature Stop ENU
sa10890 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15775 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dnajb12a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dnajb12a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to misfolded protein (more)
    Cellular Component integral component of membrane (more)
    Molecular Function Hsp70 protein binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dnajb12a-201 (1)    Ensembl 2081
    dnajb12a-202 (1)    Ensembl 721
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dnajb12a No data available
    MARKER RELATIONSHIPS
    dnajb12a Contained in: [BAC] DKEYP-115D2 (1)
    dnajb12a Encodes: [EST] fc16f06, fi38b10
    [cDNA] MGC:63739 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212659 (1) 2046 bp
    Genomic GenBank:AL929344 (1) 190898 bp
    Select Tool
    Polypeptide UniProtKB:Q7SXR2 (1) 371 aa
    Sequence Clusters UniGene:11550 (1)
    Sequence Information (all 13)
    ORTHOLOGY for dnajb12a ( Chr: 13 )
    CITATIONS (24)