Gene
add3a
- ID
- ZDB-GENE-030131-2721
- Name
- adducin 3 (gamma) a
- Symbol
- add3a Nomenclature History
- Previous Names
-
- add3
- wu:fb38g03
- wu:fc16e06
- zgc:55560
- zgc:77226
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity; spectrin binding activity; and structural molecule activity. Involved in hepaticobiliary system development. Predicted to localize to cytoskeleton; plasma membrane raft; and postsynaptic density. Is expressed in head; liver; pericardial region; and pleuroperitoneal region. Used to study biliary atresia. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 50. Orthologous to human ADD3 (adducin 3).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
spastic quadriplegic cerebral palsy 3 | Alliance | Cerebral palsy, spastic quadriplegic, 3 | 617008 |
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
biliary atresia | add3asa819/sa819 | standard conditions | Tang et al., 2016 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Aldolase class II Adducin subfamily | Class II aldolase/adducin N-terminal | Class II aldolase/adducin N-terminal domain superfamily |
---|---|---|---|---|
UniProtKB:A0A8M6YXA3
|
677 | |||
UniProtKB:Q1LUP1
|
672 | |||
UniProtKB:A0A2R8QBF8
|
671 | |||
UniProtKB:Q1LUP2
|
645 | |||
UniProtKB:Q7ZUA1
|
672 | |||
UniProtKB:A0A8M6Z434
|
651 | |||
UniProtKB:A0A2R8Q5P5
|
678 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
add3a-201
(1)
|
Ensembl | 2502 nt | |
mRNA |
add3a-202
(1)
|
Havana | 3671 nt | |
mRNA |
add3a-203
(1)
|
Havana | 3494 nt | |
mRNA |
add3a-205
(1)
|
Havana | 871 nt | |
mRNA |
add3a-206
(1)
|
Havana | 612 nt | |
mRNA |
add3a-207
(1)
|
Havana | 570 nt | |
mRNA |
add3a-208
(1)
|
Ensembl | 2044 nt | |
mRNA |
add3a-209
(1)
|
Ensembl | 2148 nt | |
mRNA |
add3a-210
(1)
|
Ensembl | 2661 nt | |
mRNA |
add3a-211
(1)
|
Ensembl | 2261 nt | |
mRNA |
add3a-212
(1)
|
Ensembl | 3034 nt | |
ncRNA |
add3a-005
(1)
|
Havana | 849 nt |
Interactions and Pathways
No data available
Plasmids
No data available