Gene

add3a

ID
ZDB-GENE-030131-2721
Name
adducin 3 (gamma) a
Symbol
add3a Nomenclature History
Previous Names
  • add3
  • wu:fb38g03
  • wu:fc16e06
  • zgc:55560
  • zgc:77226
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity; spectrin binding activity; and structural molecule activity. Involved in hepaticobiliary system development. Predicted to localize to cytoskeleton; plasma membrane raft; and postsynaptic density. Is expressed in head; liver; pericardial region; and pleuroperitoneal region. Used to study biliary atresia. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 50. Orthologous to human ADD3 (adducin 3).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With add3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cerebral palsy, spastic quadriplegic, 3 617008
Associated With add3a Via Experimental Models
Human Disease Fish Conditions Citations
biliary atresia add3asa819/sa819 standard conditions Tang et al., 2016
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001303 Class II aldolase/adducin N-terminal
Family IPR027772 Gamma-adducin
Homologous_superfamily IPR036409 Class II aldolase/adducin N-terminal domain superfamily
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations