ZFIN ID: ZDB-GENE-030131-271
Gene Name: slow myosin heavy chain 1
Gene Symbol: smyhc1
Sequence Ontology ID : SO:0000704

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Previous Names: smhc1 (1), fb18g10, im:6897999, wu:fb18g10

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 97 figures from 42 publications
Directly Submitted Expression Data: 12 figures (16 images) from Rauch et al., 2003 [fb18g10]
  7 figures (37 images) from Thisse et al., 2004 [IMAGE:6897999]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Juvenile:Days 30-44 (30d-45d, 10 mm, adult fins/pigment)
  abductor hyohyoid, adaxial cell, adductor mandibulae, adductor operculi (all 36) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12384 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24569 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30154 Point Mutation Unknown Premature Stop ENU
    sa30155 Point Mutation Unknown Splice Site ENU
    sa30156 Point Mutation Unknown Premature Stop ENU
    sa37966 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-smyhc1 (1), MO2-smyhc1 (1)
    PHENOTYPE
    Data: 5 figures from 2 publications
    Observed in: myosin filament assembly, skeletal muscle Z disc, slow muscle cell striated muscle myosin thick filament, slow muscle cell striated muscle thin filament (all 5) expand
    DISEASE ASSOCIATED WITH smyhc1 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process slow-twitch skeletal muscle fiber contraction (more)
    Cellular Component myosin complex (more)
    Molecular Function ATP binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000048 (1)
  • InterPro:IPR001609 (1)
  • InterPro:IPR002928 (1)
  • InterPro:IPR004009 (1)
  • InterPro:IPR008989 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS50096 (1)
  • PROSITE:PS51456 (1)
  • Pfam:PF00063 (1)
  • Pfam:PF01576 (1)
  • Pfam:PF02736 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smyhc1-001 (1) 6575
    smyhc1-002 (1) 516
    ncRNA smyhc1-003 (1) 705
    smyhc1-004 (1) 830
    smyhc1-005 (1) 700
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM smyhc1
    Tg(smyhc1:EGFP), Tg(smyhc1:GCaMP3), Tg(smyhc1:LY-Tomato), Tg(smyhc1:mCherry-CAAX), Tg(smyhc1:musk-002-MYC) (all 9) expand
    MARKER RELATIONSHIPS
    smyhc1Contained in: [BAC] CH211-24N20 (1) (order this)
    smyhc1Encodes: [EST] fb18g10 (order this), IMAGE:6897999 (1) (order this)
    [cDNA] MGC:194801 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020507 (1) 5905bp
    Genomic GenBank:CU929259 (1) 195306bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IVW7 (1) 1939aa
    Sequence Clusters UniGene:161747 (1)
    Sequence Information (all 35)
    OTHER smyhc1 GENE PAGES
  • Alliance (1)
  • Gene:321552 (1)
  • VEGA:OTTDARG00000034809 (1)
  • Ensembl(GRCz10):ENSDARG00000099959 (1)
  • ORTHOLOGY for smyhc1 (Chr: 24)
    CITATIONS (87)