Gene

prpf19

ID
ZDB-GENE-030131-263
Name
pre-mRNA processing factor 19
Symbol
prpf19 Nomenclature History
Previous Names
  • prp19
  • fb18f09
  • wu:fb18f09
  • zgc:56158 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have ubiquitin-protein transferase activity. Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to localize to Prp19 complex; U2-type catalytic step 1 spliceosome; and catalytic step 2 spliceosome. Orthologous to human PRPF19 (pre-mRNA processing factor 19).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prpf19 Human Ortholog
No data available
Associated With prpf19 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR000772 Ricin B, lectin domain
Domain IPR003613 U box domain
Domain IPR013915 Pre-mRNA-splicing factor 19
Domain IPR017986 WD40-repeat-containing domain
Family IPR038959 Pre-mRNA-processing factor 19
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR020472 G-protein beta WD-40 repeat
Domain Details Per Protein
Protein Length G-protein beta WD-40 repeat Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor 19 Ricin B, lectin domain U box domain WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily Zinc finger, RING/FYVE/PHD-type
UniProtKB:Q7ZV92 505
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations