ZFIN ID: ZDB-GENE-030131-2603
Gene Name: cullin 1a
Gene Symbol: cul1a    Nomenclature History

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Previous Names: wu:fc13a10, zgc:77500

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have ubiquitin protein ligase binding activity and ubiquitin-protein transferase activity. Involved in neutrophil chemotaxis. Predicted to localize to SCF ubiquitin ligase complex. Orthologous to human CUL1 (cullin 1).
Genome Resources: Alliance (1),  Gene:323883 (1),  Ensembl(GRCz11):ENSDARG00000019239 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55747]
  1 figure (1 image) from Thisse et al., 2005 [eu172]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015007Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33046 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cul1a
    1
    CRISPR2-cul1a
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cul1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cul1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neutrophil chemotaxis (more)
    Cellular Component cullin-RING ubiquitin ligase complex (more)
    Molecular Function ubiquitin protein ligase binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cul1a-201 (1)    Ensembl 3385
    ncRNA cul1a-002 (1)    Ensembl 991
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cul1a No data available
    MARKER RELATIONSHIPS
    cul1a Contained in: [BAC] CH211-120F16 (1)
    cul1a Encodes: [EST] eu172 (1), fc13a10
    [cDNA] MGC:55747 (1), MGC:77500 (1), MGC:192752 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199659 (1) 3385 nt
    Genomic GenBank:BX927101 (1) 162145 nt
    Select Tool
    Polypeptide UniProtKB:Q6NYS3 (1) 777 aa
    Sequence Information (all 20)
    ORTHOLOGY for cul1a ( Chr: 2 )
    CITATIONS (27)