ZFIN ID: ZDB-GENE-030131-2581
Gene Name: nuclear receptor binding SET domain protein 2
Gene Symbol: nsd2
Sequence Ontology ID : SO:0000704

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Previous Names: fc12c04, si:rp71-77d7.2, whsc1, wu:fc12c04, wu:fi20c01

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 3 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [IMAGE:7158283]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, central nervous system, eye, fin (all 16) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
scu1 Indel Unknown Unknown CRISPR
Targeting reagents: CRISPR1-nsd2 (1), MO1-nsd2 (1), MO2-nsd2 (1), MO3-nsd2 (1)
PHENOTYPE
Data: 4 figures from Yamada-Okabe et al., 2010
Observed in: bone development, brain, cartilage element, ceratobranchial cartilage (all 10) expand
DISEASE ASSOCIATED WITH nsd2 HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cartilage development (more)
Cellular Component nucleus (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • EC:2.1.1.43 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA whsc1-001 (1) 5357
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nsd2 No data available
    MARKER RELATIONSHIPS
    nsd2Contained in: [BAC] CH211-195N12 (1) (order this), CH211-233A24 (1) (order this)
    nsd2Encodes: [EST] fc12c04, fi20c01, IMAGE:7158283 (1) (order this)
    [cDNA] MGC:198423 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001082551 (1) 5347bp
    Genomic RefSeq:NW_018395307 (1)
    Select Tool
    Polypeptide UniProtKB:B7ZVT1 (1) 1461aa
    Sequence Clusters UniGene:78031 (1)
    Sequence Information (all 45)
    OTHER nsd2 GENE PAGES
  • Alliance (1)
  • Gene:100000709 (1)
  • VEGA:OTTDARG00000023818 (1)
  • Ensembl(GRCz10):ENSDARG00000026225 (1)
  • ORTHOLOGY for nsd2 (Chr: 13)
    CITATIONS (23)