ZFIN ID: ZDB-GENE-030131-2576
Gene Name: transglutaminase 2b
Gene Symbol: tgm2b    Nomenclature History

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Previous Names: fc12b04, wu:fc12b04, zgc:136700

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking. Predicted to localize to mitochondrion. Is expressed in notochord. Orthologous to human TGM2 (transglutaminase 2).
Genome Resources: Alliance (1),  Gene:323856 (1),  Ensembl(GRCz11):ENSDARG00000074094 (2)
GENE EXPRESSION
All Expression Data: 9 figures from 3 publications
Directly Submitted Expression Data: 6 figures (1 image) from Thisse et al., 2005 [eu541]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015838Tg Transgenic Insertion Unknown Unknown DNA
sa40619 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tgm2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tgm2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process peptide cross-linking (more)
    Cellular Component mitochondrion (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tgm2b-202 (1)    Ensembl 1648
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tgm2b No data available
    MARKER RELATIONSHIPS
    tgm2b Contained in: [Fosmid] CH1073-441C13 (1)
    tgm2b Encodes: [EST] eu541 (1), fc12b04
    [cDNA] MGC:136700 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212656 (1) 2479 nt
    Genomic GenBank:CU634004 (1) 34760 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8PX12 (1) 681 aa
    Sequence Information (all 20)
    ORTHOLOGY for tgm2b ( Chr: 6 )
    CITATIONS (29)