Gene

nradd

ID
ZDB-GENE-030131-2537
Name
neurotrophin receptor associated death domain
Symbol
nradd Nomenclature History
Previous Names
  • ngfr
  • NGFRb (1)
  • wu:fb38c02
  • wu:fc10h01
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have coreceptor activity; death receptor activity; and nerve growth factor binding activity. Predicted to be involved in Rho protein signal transduction. Predicted to localize to cell surface and plasma membrane.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Ozalp et al., 2021
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nradd Human Ortholog
No data available
Associated With nradd Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000488 Death domain
Domain IPR001368 TNFR/NGFR cysteine-rich region
Domain IPR034046 Tumor necrosis factor receptor 16, N-terminal
Domain IPR041448 Tumor necrosis factor receptor member 16, transmembrane domain
Homologous_superfamily IPR011029 Death-like domain superfamily
Domain Details Per Protein
Protein Length Death domain Death-like domain superfamily TNFR/NGFR cysteine-rich region Tumor necrosis factor receptor 16, N-terminal Tumor necrosis factor receptor member 16, transmembrane domain
UniProtKB:E7F8D4 413
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Eimon, et al. (2006. Cell Death Differ. 13:1619-1630.) reported orthology to human NGFR supported by amino acid sequence identity.
Citations