ZFIN ID: ZDB-GENE-030131-2459
Gene Name: selenoprotein U 1a
Gene Symbol: selenou1a
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: selu1 (1), selU (1), sepu, fam213a, fam213aa (1), fc08d10, wu:fb06a02, wu:fc08d10, zgc:73311

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
Note: Despite AA similarity and sytenic evidence, the fam213a genes were renamed as selenoprotein u genes because Castellano et al. (2004) demonstrated that unique selenocysteine-containing selenoproteins occur in fish and chicken, but not mammals or worms. The selenoprotein U genes in zebrafish contain these selenocyteine codons, along with the selenocysteine insertion sequence, making them distinct from similar mammalian genes.
AUTOMATED DESCRIPTION
Predicted to have antioxidant activity; predicted to be involved in oxidation-reduction process; predicted to localize to the cytoplasm; orthologous to human PRXL2A (peroxiredoxin like 2A).
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:73311]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13116 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42175 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH selenou1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH selenou1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cytoplasm (more)
    Molecular Function antioxidant activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000866 (1)
  • InterPro:IPR032801 (1)
  • InterPro:IPR032802 (1)
  • InterPro:IPR036249 (1)
  • Pfam:PF00578 (1)
  • Pfam:PF13911 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fam213aa-001 (1) 1291
    fam213aa-002 (1) 790
    fam213aa-003 (1) 334
    fam213aa-004 (1) 354
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM selenou1a No data available
    MARKER RELATIONSHIPS
    selenou1aContained in: [BAC] DKEY-250O4 (1) (order this)
    selenou1aContains: [SNP] rs3728750 (1), rs3728751 (1)
    selenou1aEncodes: [EST] fb06a02, fc08d10
    [cDNA] MGC:73311 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200036 (1) 1250bp
    Genomic GenBank:BX927129 (1) 154491bp
    Select Tool
    Polypeptide UniProtKB:Q6PBP3 (1) 212aa
    Sequence Clusters UniGene:75659 (1)
    Sequence Information (all 28)
    OTHER selenou1a GENE PAGES
  • Alliance (1)
  • Gene:323739 (1)
  • VEGA:OTTDARG00000022746 (1)
  • ORTHOLOGY for selenou1a (Chr: 13)
    CITATIONS (24)