ZFIN ID: ZDB-GENE-030131-2438
Gene Name: oxidation resistance 1b
Gene Symbol: oxr1b    Nomenclature History

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Previous Names: fc07g10, si:dkeyp-84f11.5, wu:fc07g10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to be involved in negative regulation of oxidative stress-induced neuron death and response to oxidative stress. Predicted to localize to nucleolus. Is expressed in central nervous system; head; lateral line ganglion; and olfactory pit. Human ortholog(s) of this gene implicated in cerebellar hyplasia/atrophy, epilepsy, and global developmental delay. Orthologous to human OXR1 (oxidation resistance 1).
Genome Resources: Alliance (1),  Gene:570476 (1),  Ensembl(GRCz11):ENSDARG00000063310 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa45656 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH oxr1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    cerebellar hyplasia/atrophy, epilepsy, and global developmental delay Alliance Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay 213000
    DISEASE ASSOCIATED WITH oxr1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of oxidative stress-induced neuron death (more)
    Cellular Component nucleolus (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA oxr1b-201 (1)    Ensembl 954
    oxr1b-203 (1)    Ensembl 4065
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM oxr1b No data available
    MARKER RELATIONSHIPS
    oxr1b Contained in: [BAC] CH73-216M24 (1), CH73-312O15 (1), DKEYP-84F11 (1)
    oxr1b Encodes: [EST] fc07g10
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045203 (1) 3660 nt
    Genomic GenBank:BX890617 182182 nt
    Select Tool
    Polypeptide UniProtKB:I3ISS4 (1) 841 aa
    Sequence Information (all 20)
    ORTHOLOGY for oxr1b ( Chr: 19 )
    CITATIONS (16)