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Gene

her8a

ID
ZDB-GENE-030131-2376
Name
hairy-related 8a
Symbol
her8a Nomenclature History
Previous Names
  • her8b (1)
  • wu:fb75f05 (1)
  • wu:fc06c04 (1)
  • zgc:85712 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within glial cell differentiation; negative regulation of neurogenesis; and neuron differentiation. Located in chromatin. Is expressed in several structures, including anterior neural keel; anterior neural rod; central nervous system; neural tube; and posterior neural keel.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With her8a Human Ortholog
No data available
Associated With her8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003650 Orange domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Orange domain
UniProtKB:F1R6H0
UniProtKB:Q9DEU7 221
UniProtKB:Q9DEU8 221
UniProtKB:F1QI81 221
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations