Gene

itm2ba

ID
ZDB-GENE-030131-2352
Name
integral membrane protein 2Ba
Symbol
itm2ba Nomenclature History
Previous Names
  • itm2b
  • wu:fc05f02
  • zgc:55770
  • zgc:85688
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have amyloid-beta binding activity. Predicted to be involved in negative regulation of amyloid precursor protein biosynthetic process. Predicted to localize to Golgi apparatus and plasma membrane. Human ortholog(s) of this gene implicated in ITM2B-related cerebral amyloid angiopathy 1 and ITM2B-related cerebral amyloid angiopathy 2. Orthologous to human ITM2B (integral membrane protein 2B).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itm2ba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
ITM2B-related cerebral amyloid angiopathy 1 Alliance Dementia, familial British 176500
ITM2B-related cerebral amyloid angiopathy 2 Alliance Dementia, familial Danish 117300
?Retinal dystrophy with inner retinal dysfunction and ganglion cell abnormalities 616079
Associated With itm2ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007084 BRICHOS domain
Family IPR040145 Integral membrane protein 2
Domain Details Per Protein
Protein Length BRICHOS domain Integral membrane protein 2
UniProtKB:Q803H7 261
UniProtKB:Q6NV09 261
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations