si:ch211-241e1.3

ID

ZDB-GENE-030131-230

Name

si:ch211-241e1.3

Symbol

si:ch211-241e1.3 Nomenclature History

Previous Names

fb17h02
wu:fb17h02

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable signaling receptor binding activity. Predicted to be involved in several processes, including axon guidance; basement membrane assembly; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within several processes, including cell adhesion; regulation of cell migration; and regulation of embryonic development. Predicted to be located in basement membrane and extracellular region. Predicted to be part of laminin complex. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and lung small cell carcinoma. Orthologous to human LAMA3 (laminin subunit alpha 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Nagendran et al., 2015

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With si:ch211-241e1.3 Human Ortholog

No data available

Associated With si:ch211-241e1.3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001791	Laminin G domain
Domain	IPR002049	Laminin-type EGF domain
Domain	IPR009254	Laminin alpha, domain I
Domain	IPR010307	Laminin domain II
Family	IPR050440	Laminin/Netrin Extracellular Matrix
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily