Gene

col4a5

ID
ZDB-GENE-030131-2281
Name
collagen, type IV, alpha 5 (Alport syndrome)
Symbol
col4a5 Nomenclature History
Previous Names
  • dragnet (1)
  • drg
  • wu:fc02g11
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to be an extracellular matrix structural constituent. Involved in axonogenesis and basement membrane organization. Predicted to localize to basement membrane and extracellular space. Is expressed in several structures, including digestive system; integument; nervous system; neural tube; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Alport syndrome and X-linked Alport syndrome. Orthologous to human COL4A5 (collagen type IV alpha 5 chain).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With col4a5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked Alport syndrome Alliance Alport syndrome 1, X-linked 301050
Associated With col4a5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001442 Collagen IV, non-collagenous
Homologous_superfamily IPR016187 C-type lectin fold
Homologous_superfamily IPR036954 Collagen IV, non-collagenous domain superfamily
Repeat IPR008160 Collagen triple helix repeat
Domain Details Per Protein
Protein Length Collagen IV, non-collagenous Collagen IV, non-collagenous domain superfamily Collagen triple helix repeat C-type lectin fold
UniProtKB:B0UXF7 1679
UniProtKB:A0A1L1QZI9 1659
UniProtKB:Q4TZX0 237
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations