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ZIRC
ZFIN ID: ZDB-GENE-030131-2248
Gene Name: DENN/MADD domain containing 5B
Gene Symbol: dennd5b    Nomenclature History

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Previous Names: id:ibd5082, wu:fc01g04, zgc:77218

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have Rab guanyl-nucleotide exchange factor activity. Predicted to localize to the integral component of membrane. Is expressed in neural plate and tail bud. Orthologous to human DENND5B (DENN domain containing 5B).
Genome Resources: Alliance (1),  Gene:323528 (1),  Ensembl(GRCz11):ENSDARG00000003789 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 3 figures (4 images) from Kudoh et al., 2001 [ibd5082]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024449Tg Transgenic Insertion Unknown Unknown DNA
la028980Tg Transgenic Insertion Unknown Unknown DNA
sa10610 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11630 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31391 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dennd5b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dennd5b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process calcium ion transmembrane transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function Rab guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 5)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dennd5b-203 (1)    Ensembl 456
    dennd5b-204 (1)    Ensembl 5510
    dennd5b-205 (1)    Ensembl 923
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dennd5b No data available
    MARKER RELATIONSHIPS
    dennd5b Contained in: [BAC] CH211-11C20 (1) (order this)
    dennd5b Encodes: [EST] fc01g04, ibd5082 (1) (order this)
    [cDNA] MGC:77218 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212644 (1) 5600 bp
    Genomic GenBank:BX001012 (1) 158481 bp
    Select Tool
    Polypeptide UniProtKB:F1QQ55 (1) 1325 aa
    Sequence Clusters UniGene:77167 (1)
    Sequence Information (all 26)
    ORTHOLOGY for dennd5b ( Chr: 4 )
    CITATIONS (26)