ZFIN ID: ZDB-GENE-030131-2248
Gene Name: DENN/MADD domain containing 5B
Gene Symbol: dennd5b
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: id:ibd5082, wu:fc01g04, zgc:77218

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have Rab guanyl-nucleotide exchange factor activity; predicted to localize to the integral component of membrane; orthologous to human DENND5B (DENN domain containing 5B).
GENE EXPRESSION
Directly Submitted Expression Data: 3 figures (4 images) from Kudoh et al., 2001 [ibd5082]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024449Tg Transgenic Insertion Unknown Unknown DNA
la028980Tg Transgenic Insertion Unknown Unknown DNA
sa10610 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11630 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31391 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dennd5b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dennd5b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process detection of mechanical stimulus (more)
    Cellular Component integral component of membrane (more)
    Molecular Function Rab guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001024 (1)
  • InterPro:IPR001194 (1)
  • InterPro:IPR004012 (1)
  • InterPro:IPR005112 (1)
  • InterPro:IPR005113 (1)
  • InterPro:IPR036392 (1)
  • InterPro:IPR037213 (1)
  • InterPro:IPR037516 (1)
  • PROSITE:PS50095 (1)
  • PROSITE:PS50211 (1)
  • PROSITE:PS50826 (1)
  • Pfam:PF01477 (1)
  • Pfam:PF02141 (1)
  • Pfam:PF02759 (1)
  • Pfam:PF03455 (1)
  • Pfam:PF03456 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dennd5b-203 (1) 456
    dennd5b-204 (1) 5510
    dennd5b-205 (1) 923
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dennd5b No data available
    MARKER RELATIONSHIPS
    dennd5bContained in: [BAC] CH211-11C20 (1) (order this)
    dennd5bEncodes: [EST] fc01g04, ibd5082 (1) (order this)
    [cDNA] MGC:77218 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212644 (1) 5600bp
    Genomic GenBank:BX001012 (1) 158481bp
    Select Tool
    Polypeptide UniProtKB:F1QQ55 (1) 1325aa
    Sequence Clusters UniGene:77167 (1)
    Sequence Information (all 26)
    OTHER dennd5b GENE PAGES
  • Alliance (1)
  • Gene:323528 (1)
  • VEGA:OTTDARG00000008102 (1)
  • Ensembl(GRCz11):ENSDARG00000003789 (2)
  • ORTHOLOGY for dennd5b (Chr: 4)
    CITATIONS (25)