Gene

bmi1a

ID
ZDB-GENE-030131-224
Name
bmi1 polycomb ring finger oncogene 1a
Symbol
bmi1a Nomenclature History
Previous Names
  • bmi1
  • pcgf4 (1)
  • psc1 (1)
  • wu:fb17g03
  • wu:fd18f06
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have promoter-specific chromatin binding activity. Involved in cerebellum development; hematopoietic stem cell migration; and primitive hemopoiesis. Predicted to localize to PRC1 complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia; colorectal carcinoma; and hepatocellular carcinoma. Is expressed in eye; gonad; and midbrain hindbrain boundary. Orthologous to several human genes including COMMD3-BMI1 (COMMD3-BMI1 readthrough).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bmi1a Human Ortholog
No data available
Associated With bmi1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR001841 Zinc finger, RING-type
Domain IPR032443 RAWUL domain
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length RAWUL domain Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site
UniProtKB:A0A0R4I9F7 322
UniProtKB:Q8JIR0 320
UniProtKB:E9QBX8 81
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations