header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-2211
Gene Name: complement component c3b, tandem duplicate 1
Gene Symbol: c3b.1
Sequence Ontology ID : SO:0001217

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: c3.7 (1), si:dkey-21e7.2, wu:fb99g02

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have endopeptidase inhibitor activity. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including complement deficiency  ...
GENE EXPRESSION
All Expression Data: 2 figures from Forn-CunĂ­ et al., 2014
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH c3b.1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
age related macular degeneration 9 {Macular degeneration, age-related, 9} 611378
complement component 3 deficiency C3 deficiency 613779
{Hemolytic uremic syndrome, atypical, susceptibility to, 5} 612925
DISEASE ASSOCIATED WITH c3b.1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component extracellular region (more)
Molecular Function endopeptidase inhibitor activity (more)
GO Terms (all 3)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA c3b.1-201 (1) 5813
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM c3b.1 No data available
MARKER RELATIONSHIPS
c3b.1 Contained in: [BAC] CH211-140F21 (1) (order this), DKEY-21E7 (1) (order this)
c3b.1 Encodes: [EST] fb99g02
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001100013 (1) 5043 bp
Genomic GenBank:BX649330 (1) 163964 bp
Select Tool
Polypeptide UniProtKB:A0A0N4SU63 (1) 1681 aa
Sequence Clusters UniGene:120195 (1)
Sequence Information (all 18)
ORTHOLOGY for c3b.1 ( Chr: 22 )
CITATIONS (15)