ZFIN ID: ZDB-GENE-030131-2152
Gene Name: prickle homolog 1b
Gene Symbol: prickle1b    Nomenclature History

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Previous Names: fb98c11, pk1b (1), si:ch211-155a11.1, wu:fb98c11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have zinc ion binding activity. Involved in facial nucleus development; hindbrain tangential cell migration; and motor neuron migration. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Is expressed in several structures, including mesoderm; myotome; nervous system; neuroepithelial cell; and pharyngeal arch. Orthologous to human PRICKLE1 (prickle planar cell polarity protein 1).
Genome Resources: Alliance (1),  Gene:556148 (1),  Ensembl(GRCz11):ENSDARG00000045694 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh122 Point Mutation Unknown Missense ENU
la010450Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la015329Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la015330Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024421Tg Transgenic Insertion Unknown Unknown DNA
    la024422Tg Transgenic Insertion Unknown Unknown DNA
    la024423Tg Transgenic Insertion Unknown Unknown DNA
    la024424Tg Transgenic Insertion Unknown Unknown DNA
    sa40255 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-prickle1b
    1
    MO1-prickle1b N/A 7
    MO2-prickle1b N/A 7
    DISEASE ASSOCIATED WITH prickle1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    progressive myoclonus epilepsy 1B Alliance Epilepsy, progressive myoclonic 1B 612437
    DISEASE ASSOCIATED WITH prickle1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neuron migration (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA prickle1b-202 (1)    Ensembl 922
    prickle1b-203 (1)    Ensembl 3389
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prickle1b No data available
    MARKER RELATIONSHIPS
    prickle1b Contained in: [BAC] CH211-155A11 (1)
    prickle1b Encodes: [EST] eu2482 (1), fb98c11
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001030098 (1) 3252 nt
    Genomic GenBank:AL929504 (1) 160087 nt
    Select Tool
    Polypeptide UniProtKB:F2Z4V3 (1) 872 aa
    Sequence Information (all 17)
    ORTHOLOGY for prickle1b ( Chr: 4 )
    CITATIONS (40)