Gene

ogdha

ID
ZDB-GENE-030131-2143
Name
oxoglutarate dehydrogenase a
Symbol
ogdha Nomenclature History
Previous Names
  • ogdh
  • im:7045267
  • wu:fa06d01
  • wu:fb98a04
  • zgc:73296
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have oxoglutarate dehydrogenase (succinyl-transferring) activity. Involved in heart contraction. Predicted to localize to mitochondrion and oxoglutarate dehydrogenase complex. Is expressed in several structures, including immature eye; lens; mesoderm; musculature system; and pronephric duct. Orthologous to human OGDH (oxoglutarate dehydrogenase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ogdha Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Oxoglutarate dehydrogenase deficiency 203740
Associated With ogdha Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001017 Dehydrogenase, E1 component
Domain IPR005475 Transketolase-like, pyrimidine-binding domain
Domain IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
Domain IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain
Family IPR011603 2-oxoglutarate dehydrogenase E1 component
Homologous_superfamily IPR029061 Thiamin diphosphate-binding fold
Homologous_superfamily IPR042179 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily
Domain Details Per Protein
Protein Length 2-oxoglutarate dehydrogenase E1 component 2-oxoglutarate dehydrogenase E1 component, N-terminal domain Dehydrogenase, E1 component Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily Thiamin diphosphate-binding fold Transketolase-like, pyrimidine-binding domain
UniProtKB:F1RAH0 230
UniProtKB:Q58EE8 416
UniProtKB:F1Q5B8 1019
UniProtKB:Q6PBQ6 175
UniProtKB:A0A0R4IP01 1022
UniProtKB:B8JI08 1022
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations