Gene
setd2
- ID
- ZDB-GENE-030131-2140
- Name
- SET domain containing 2, histone lysine methyltransferase
- Symbol
- setd2 Nomenclature History
- Previous Names
-
- fb97h09
- wu:fb97h09 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have histone methyltransferase activity (H3-K36 specific). Predicted to be involved in histone H3-K36 trimethylation and regulation of transcription, DNA-templated. Predicted to localize to chromosome and nucleus. Is expressed in central nervous system and intermediate cell mass of mesoderm. Orthologous to human SETD2 (SET domain containing 2, histone lysine methyltransferase).
- Genome Resources
- Note
- None
- All Expression Data
- 2 figures from Sun et al., 2008
- Cross-Species Comparison
- High Throughput Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Luscan-Lumish syndrome | 616831 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001202 | WW domain |
Domain | IPR001214 | SET domain |
Domain | IPR003616 | Post-SET domain |
Domain | IPR006560 | AWS domain |
Domain | IPR013257 | Set2 Rpb1 interacting domain |
Homologous_superfamily | IPR036020 | WW domain superfamily |
Homologous_superfamily | IPR038190 | Set2 Rpb1 interacting domain superfamily |
Domain Details Per Protein
Protein | Length | AWS domain | Post-SET domain | Set2 Rpb1 interacting domain | Set2 Rpb1 interacting domain superfamily | SET domain | WW domain | WW domain superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A2R8QDW6
|
2735 | |||||||
UniProtKB:A0A2R8Q1Y5
|
2694 | |||||||
UniProtKB:A0A2R8Q6N6
|
2650 | |||||||
UniProtKB:A5XBP8
|
175 | |||||||
UniProtKB:F1QJI9
|
2737 | |||||||
UniProtKB:Q071D9
|
369 |
Interactions and Pathways
No data available
Plasmids
No data available