Gene
sin3ab
- ID
- ZDB-GENE-030131-2066
- Name
- SIN3 transcription regulator family member Ab
- Symbol
- sin3ab Nomenclature History
- Previous Names
-
- fb95g11
- wu:fb95g11
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable transcription corepressor activity. Predicted to be involved in histone deacetylation and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of Sin3 complex. Predicted to be active in chromatin. Human ortholog(s) of this gene implicated in chromosome 15q24 deletion syndrome. Orthologous to human SIN3A (SIN3 transcription regulator family member A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
chromosome 15q24 deletion syndrome | Alliance | Witteveen-Kolk syndrome | 613406 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR013194 | Histone deacetylase interacting domain |
Domain | IPR031693 | Sin3, C-terminal |
Family | IPR037969 | Transcriptional regulatory protein Sin3a |
Family | IPR039774 | Transcriptional regulatory protein Sin3-like |
Homologous_superfamily | IPR036600 | Paired amphipathic helix superfamily |
Repeat | IPR003822 | Paired amphipathic helix |
Domain Details Per Protein
Protein | Length | Histone deacetylase interacting domain | Paired amphipathic helix | Paired amphipathic helix superfamily | Sin3, C-terminal | Transcriptional regulatory protein Sin3a | Transcriptional regulatory protein Sin3-like |
---|---|---|---|---|---|---|---|
UniProtKB:A0A1L1QZM2
|
204 | ||||||
UniProtKB:E7F0R9
|
1262 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
sin3ab-201
(1)
|
5330 nt | |
mRNA |
sin3ab-202
(1)
|
1598 nt | |
ncRNA |
sin3ab-002
(1)
|
687 nt |
Interactions and Pathways
No data available
Plasmids
No data available