Gene

sin3ab

ID
ZDB-GENE-030131-2066
Name
SIN3 transcription regulator family member Ab
Symbol
sin3ab Nomenclature History
Previous Names
  • fb95g11
  • wu:fb95g11
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable transcription corepressor activity. Predicted to be involved in histone deacetylation and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be part of Sin3 complex. Predicted to be active in chromatin. Human ortholog(s) of this gene implicated in chromosome 15q24 deletion syndrome. Orthologous to human SIN3A (SIN3 transcription regulator family member A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sin3ab Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
chromosome 15q24 deletion syndrome Alliance Witteveen-Kolk syndrome 613406
Associated With sin3ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013194 Histone deacetylase interacting domain
Domain IPR031693 Sin3, C-terminal
Family IPR037969 Transcriptional regulatory protein Sin3a
Family IPR039774 Transcriptional regulatory protein Sin3-like
Homologous_superfamily IPR036600 Paired amphipathic helix superfamily
Repeat IPR003822 Paired amphipathic helix
Domain Details Per Protein
Protein Length Histone deacetylase interacting domain Paired amphipathic helix Paired amphipathic helix superfamily Sin3, C-terminal Transcriptional regulatory protein Sin3a Transcriptional regulatory protein Sin3-like
UniProtKB:A0A1L1QZM2 204
UniProtKB:E7F0R9 1262
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations