ZFIN ID: ZDB-GENE-030131-2056
Gene Name: chloride channel 6
Gene Symbol: clcn6    Nomenclature History

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Previous Name: wu:fb95f01

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have chloride transmembrane transporter activity. Predicted to be involved in chloride transport and transmembrane transport. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human CLCN6 (chloride voltage-gated channel 6).
Genome Resources: Alliance (1),  Gene:568122 (1),  Ensembl(GRCz11):ENSDARG00000032577 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Wang et al., 2015
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2420 Point Mutation Unknown Premature Stop ENU
sa5777 Point Mutation Unknown Premature Stop ENU
sa16118 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH clcn6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH clcn6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chloride transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function voltage-gated chloride channel activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA clcn6-201 (1)    Ensembl 3082
    ncRNA clcn6-002 (1)    Ensembl 532
    clcn6-003 (1)    Ensembl 702
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM clcn6 No data available
    MARKER RELATIONSHIPS
    clcn6 Contained in: [BAC] CH211-215J19 (1)
    clcn6 Encodes: [EST] fb95f01
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009304277 (1)
    Genomic GenBank:BX323876 (1) 218043 nt Blast at MegaBLAST
    Polypeptide UniProtKB:E7F798 (1) 863 aa
    Sequence Information (all 9)
    ORTHOLOGY for clcn6 ( Chr: 8 )
    CITATIONS (17)