ZFIN ID: ZDB-GENE-030131-2049
Gene Name: methionine adenosyltransferase II, alpha a
Gene Symbol: mat2aa    Nomenclature History

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Previous Names: mat2a (1), fd12a12, si:ch73-340n8.1, wu:fb95e01, wu:fd12a12 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have methionine adenosyltransferase activity. Involved in cardiac muscle cell development and cardiovascular system development. Predicted to localize to cytosol and methionine adenosyltransferase complex. Is expressed in anterior neural tube; epiphysis; heart; optic cup; and somite. Orthologous to human MAT2A (methionine adenosyltransferase 2A).
Genome Resources: Alliance (1),  Gene:323329 (1),  Ensembl(GRCz11):ENSDARG00000040334 (2)
GENE EXPRESSION
All Expression Data: 11 figures from 4 publications
Directly Submitted Expression Data: 7 figures (9 images) from Thisse et al., 2004 [MGC:56664]
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14309 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16647 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34836 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • xu0364Gt Transgenic Insertion Intron 1 Unknown DNA
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mat2aa N/A 1
    MO2-mat2aa N/A 1
    DISEASE ASSOCIATED WITH mat2aa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mat2aa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardiac muscle cell development (more)
    Cellular Component cytosol (more)
    Molecular Function ATP binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mat2aa-202 (1)    Ensembl 1843
    ncRNA mat2aa-002 (1)    Ensembl 862
    mat2aa-004 (1)    Ensembl 551
    mat2aa-006 (1)    Ensembl 766
    mat2aa-007 (1)    Ensembl 643
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mat2aa No data available
    MARKER RELATIONSHIPS
    mat2aa Contained in: [BAC] CH73-340N8
    mat2aa Contains: [SNP] rs3728287 (1), rs3728288 (1), rs3728289 (1), rs3728290 (1)
    mat2aa Encodes: [EST] fb95e01, fd12a12
    mat2aa Has Artifact: [cDNA] MGC:56664 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212637 (1) 2618 nt
    Genomic GenBank:BX511234 (1) 112069 nt
    Select Tool
    Polypeptide UniProtKB:F1QYU7 (1) 395 aa
    Sequence Information (all 15)
    ORTHOLOGY for mat2aa ( Chr: 10 )
    CITATIONS (40)