Gene
cicb
- ID
- ZDB-GENE-030131-1966
- Name
- capicua transcriptional repressor b
- Symbol
- cicb Nomenclature History
- Previous Names
-
- cic
- wu:fb93c01
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity. Involved in primitive erythrocyte differentiation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 45. Is expressed in head and hindbrain neural rod. Orthologous to human CIC (capicua transcriptional repressor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Huang et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 45 | Alliance | Intellectual developmental disorder, autosomal dominant 45 | 617600 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Domain of unknown function DUF4819 | High mobility group box domain | High mobility group box domain superfamily |
|---|---|---|---|---|
|
UniProtKB:F1Q6M9
|
2623 | |||
|
UniProtKB:A0A8M2BKS2
|
1398 | |||
|
UniProtKB:A0A8M2BKS3
|
2632 |
Interactions and Pathways
No data available
Plasmids
No data available