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Gene

cicb

ID
ZDB-GENE-030131-1966
Name
capicua transcriptional repressor b
Symbol
cicb Nomenclature History
Previous Names
  • cic
  • wu:fb93c01
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within primitive erythrocyte differentiation. Predicted to be active in nucleus. Is expressed in head and hindbrain neural rod. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 45. Orthologous to human CIC (capicua transcriptional repressor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Chen et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Huang et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cicb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant mental retardation 45 Alliance Mental retardation, autosomal dominant 45 617600
Associated With cicb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009071 High mobility group box domain
Domain IPR032147 Domain of unknown function DUF4819
Homologous_superfamily IPR036910 High mobility group box domain superfamily
Domain Details Per Protein
Protein Length Domain of unknown function DUF4819 High mobility group box domain High mobility group box domain superfamily
UniProtKB:A0A2R8QBF3 1224
UniProtKB:F1Q6M9 2623
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations