ZFIN ID: ZDB-GENE-030131-1959
Gene Name: general transcription factor IIH, polypeptide 2
Gene Symbol: gtf2h2    Nomenclature History

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Previous Names: p44 (1), wu:fb93b01

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in nucleotide-excision repair and regulation of transcription by RNA polymerase II. Predicted to localize to transcription factor TFIIH holo complex. Orthologous to several human genes including GTF2H2C (GTF2H2 family member C).
Genome Resources: Alliance (1),  Gene:323239 (1),  Ensembl(GRCz11):ENSDARG00000016514 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55599]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7162001]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20423 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20424 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gtf2h2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gtf2h2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to DNA damage stimulus (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gtf2h2-201 (1)    Ensembl 1888
    ncRNA gtf2h2-002 (1)    Ensembl 1848
    gtf2h2-003 (1)    Ensembl 796
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gtf2h2 No data available
    MARKER RELATIONSHIPS
    gtf2h2 Contained in: [BAC] CH211-214J8 (1)
    gtf2h2 Contains: [SNP] rs3727842 (1), rs3727843 (1)
    gtf2h2 Encodes: [EST] fb93b01, IMAGE:7162001 (1)
    [cDNA] MGC:55599 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201581 (1) 1905 nt
    Genomic GenBank:BX510923 (1) 165838 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZVV4 (1) 392 aa
    Sequence Information (all 11)
    ORTHOLOGY for gtf2h2 ( Chr: 5 )
    CITATIONS (25)