ZFIN ID: ZDB-GENE-030131-1826
Gene Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Gene Symbol: ace
Previous Names: fb81h03, si:ch211-124e16.1, wu:fb81h03 (1)
Location: Chr: 12 Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 12 figures (18 images) from Rauch et al., 2003 [fb64c02]
  11 figures (14 images) from Rauch et al., 2003 [fb81h03]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  adaxial cell, digestive system, endocrine system, eye (all 8) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa12049 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17717 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-ace (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ace HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Alzheimer's disease {Alzheimer disease, susceptibility to} 104300
    [Angiotensin I-converting enzyme, benign serum increase]
    {SARS, progression of}
    {Myocardial infarction, susceptibility to}
    Renal tubular dysgenesis 267430
    {Stroke, hemorrhagic} 614519
    {Microvascular complications of diabetes 3} 612624
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function carboxypeptidase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001548 (1)
  • Pfam:PF01401 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ace-001 (1) 4260
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ace No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    aceContained in: [BAC] CH211-124E16 (1) (order this), CH211-271E19 (1) (order this)
    aceEncodes: [EST] fb64c02 (1) (order this), fb81h03 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_689244 (1) 4281bp
    Genomic GenBank:CU459092 (1) 147841bp
    Select Tool
    Polypeptide UniProtKB:E7FFA5 (1) 1324aa
    Sequence Clusters UniGene:4864 (1)
    Sequence Information (all 12)
    OTHER ace GENE PAGES
  • Gene:565980 (1)
  • VEGA:OTTDARG00000035735 (1)
  • Ensembl(GRCz10):ENSDARG00000079166 (1)
  • ORTHOLOGY for ace (Chr: 12)
    Species Symbol Chromosome Accession # Evidence
    Human ACE 17
  • Gene:1636
  • OMIM:106180
  • HGNC:2707
  • Amino acid sequence comparison (1)
    Mouse Ace 11
  • MGI:87874
  • Gene:11421
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (16)