Gene

ace

ID
ZDB-GENE-030131-1826
Name
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Symbol
ace Nomenclature History
Previous Names
  • fb81h03
  • si:ch211-124e16.1
  • wu:fb81h03 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have dipeptidyl-peptidase activity; metallopeptidase activity; and peptidyl-dipeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular space and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetes mellitus (multiple); hematologic cancer (multiple); lung disease (multiple); and nephritis (multiple). Is expressed in several structures, including adaxial cell; digestive system; endocrine system; eye; and pectoral fin. Orthologous to human ACE (angiotensin I converting enzyme).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
24 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ace Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Renal tubular dysgenesis 267430
[Angiotensin I-converting enzyme, benign serum increase]
{Microvascular complications of diabetes 3} 612624
{Myocardial infarction, susceptibility to}
{SARS, progression of}
{Stroke, hemorrhagic} 614519
Associated With ace Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001548 Peptidase M2, peptidyl-dipeptidase A
Domain Details Per Protein
Protein Length Peptidase M2, peptidyl-dipeptidase A
UniProtKB:E7FFA5 1324
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations