Gene

ace

ID
ZDB-GENE-030131-1826
Name
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Symbol
ace Nomenclature History
Previous Names
  • fb81h03
  • si:ch211-124e16.1
  • wu:fb81h03 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have metallopeptidase activity and peptidyl-dipeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to plasma membrane. Is expressed in several structures, including adaxial cell; digestive system; endocrine system; eye; and pectoral fin. Human ortholog(s) of this gene implicated in several diseases, including Coronavirus infectious disease (multiple); artery disease (multiple); autoimmune disease (multiple); lung disease (multiple); and nephritis (multiple). Orthologous to human ACE (angiotensin I converting enzyme).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ace Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Renal tubular dysgenesis 267430
[Angiotensin I-converting enzyme, benign serum increase]
{Microvascular complications of diabetes 3} 612624
{Myocardial infarction, susceptibility to}
{SARS, progression of}
{Stroke, hemorrhagic} 614519
Associated With ace Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001548 Peptidase M2, peptidyl-dipeptidase A
Domain Details Per Protein
Protein Length Peptidase M2, peptidyl-dipeptidase A
UniProtKB:E7FFA5 1324
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations