ZFIN ID: ZDB-GENE-030131-1600
Gene Name: EWS RNA-binding protein 1b
Gene Symbol: ewsr1b    Nomenclature History

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Previous Names: fb40b11 (1), fusl, wu:fb40b11 (1), wu:fb75g09, zgc:55864

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have RNA binding activity and transcription coregulator activity. Involved in central nervous system neuron development and mitotic cell cycle. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Ewing sarcoma. Orthologous to human EWSR1 (EWS RNA binding protein 1).
Genome Resources: Alliance (1),  Gene:322880 (1),  Ensembl(GRCz11):ENSDARG00000020465 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55864]
  1 figure (1 image) from Thisse et al., 2004 [MGC:113929]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
DISEASE ASSOCIATED WITH ewsr1b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ewing sarcoma Alliance Ewing sarcoma 612219
Neuroepithelioma 612219
DISEASE ASSOCIATED WITH ewsr1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process central nervous system neuron development (more)
Cellular Component nucleus (more)
Molecular Function metal ion binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ewsr1b-201 (1)    Ensembl 2083
ewsr1b-202 (1)    Ensembl 2441
ewsr1b-204 (1)    Ensembl 897
ncRNA ewsr1b-003 (1)    Ensembl 1207
ewsr1b-005 (1)    Ensembl 780
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ewsr1b No data available
MARKER RELATIONSHIPS
ewsr1b Contained in: [BAC] CH211-149D1 (1)
ewsr1b Encodes: [EST] fb40b11
[cDNA] MGC:55864 (1), MGC:113929 (1), MGC:173900 (1)
ewsr1b Has Artifact: [EST] fb75g09
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_212630 (1) 2093 nt
Genomic GenBank:BX664747 (1) 188525 nt
Select Tool
Polypeptide UniProtKB:Q4QRG0 (1) 579 aa
Sequence Information (all 33)
ORTHOLOGY for ewsr1b ( Chr: 5 )
CITATIONS (27)