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General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-1571
Gene Name: formin-like 3
Gene Symbol: fmnl3    Nomenclature History

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Previous Names: fb74h11, si:ch73-60e21.1, wu:fb74h11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have GTPase activating protein binding activity. Involved in actin filament polymerization; filopodium assembly; and sprouting angiogenesis. Predicted to localize to the cytosol. Is expressed in several structures, including cardiovascular system; digestive system; myotome; nervous system; and trunk. Orthologous to human FMNL3 (formin like 3).
Genome Resources: Alliance (1),  Gene:407694 (1),  Ensembl(GRCz11):ENSDARG00000004372 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10571 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24340 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37715 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43989 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • um150 Small Deletion Unknown Frameshift, Premature Stop TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-fmnl3 N/A 3
    TALEN1-fmnl3 1
    DISEASE ASSOCIATED WITH fmnl3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fmnl3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament polymerization (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein binding (more)
    GO Terms (all 19)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fmnl3-202 (1)    Ensembl 3731
    fmnl3-203 (1)    Ensembl 1874
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fmnl3
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(UAS:fmnl3-EGFP) UAS EGFPfmnl3 Danio rerio 1 3
    MARKER RELATIONSHIPS
    fmnl3 Contained in: [BAC] CH73-60E21 (1) (order this), CH211-150A20 (1) (order this)
    fmnl3 Encodes: [EST] fb74h11
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001346154 (1)
    Genomic GenBank:CR457457 (1) 92175 bp
    Select Tool
    Polypeptide UniProtKB:Q6NXC0 (1) 1047 aa
    Sequence Clusters UniGene:77359 (1)
    Sequence Information (all 20)
    ORTHOLOGY for fmnl3 ( Chr: 23 )
    CITATIONS (21)