Gene

ddx3xa

ID
ZDB-GENE-030131-1565
Name
DEAD-box helicase 3 X-linked a
Symbol
ddx3xa Nomenclature History
Previous Names
  • ddx3
  • ddx3a
  • fb74g09
  • wu:fb74g09
  • zgc:158804
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have RNA binding activity and RNA helicase activity. Involved in neutrophil chemotaxis. Predicted to localize to P granule and nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability. Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Mueller et al., 2010
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ddx3xa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder, X-linked, syndrome, Snijders Blok type 300958
Associated With ddx3xa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
Domain IPR001650 Helicase, C-terminal
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR014014 RNA helicase, DEAD-box type, Q motif
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length ATP-dependent RNA helicase DEAD-box, conserved site DEAD/DEAH box helicase domain Helicase, C-terminal Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase RNA helicase, DEAD-box type, Q motif
UniProtKB:A2RV38 709
UniProtKB:B0S6P6 709
UniProtKB:B0S6P7 110
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations