Gene

map2k5

ID
ZDB-GENE-030131-1517
Name
mitogen-activated protein kinase kinase 5
Symbol
map2k5 Nomenclature History
Previous Names
  • fb73f02
  • wu:fb73f02 (1)
  • zgc:172137 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have MAP kinase kinase activity. Involved in brain development. Is expressed in spinal cord. Orthologous to human MAP2K5 (mitogen-activated protein kinase kinase 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Jo et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Schulte et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With map2k5 Human Ortholog
No data available
Associated With map2k5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000270 PB1 domain
Domain IPR000719 Protein kinase domain
Domain IPR034851 Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain PB1 domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A9JRD0 450
UniProtKB:B1NA67 449
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations