ZFIN ID: ZDB-GENE-030131-1452
Gene Name: arachidonate 12-lipoxygenase
Gene Symbol: alox12
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: ALOX1 (1), LOX1 (1), wu:fb72a11, zgc:64120

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits arachidonate 12-lipoxygenase activity and calcium ion binding activity; involved in oxidation-reduction process; localizes to the nucleus; orthologous to several human genes including ALOX12  ...
GENE EXPRESSION
All Expression Data: 10 figures from 4 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [MGC:64120]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7138147]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: 4 figures from Haas et al., 2011
Observed in:
DISEASE ASSOCIATED WITH alox12 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH alox12 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component nucleus (more)
Molecular Function arachidonate 12-lipoxygenase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000907 (1)
  • InterPro:IPR001024 (1)
  • InterPro:IPR001885 (1)
  • InterPro:IPR013819 (1)
  • InterPro:IPR020834 (1)
  • InterPro:IPR036226 (1)
  • InterPro:IPR036392 (1)
  • PROSITE:PS00081 (1)
  • PROSITE:PS50095 (1)
  • PROSITE:PS51393 (1)
  • Pfam:PF00305 (1)
  • Pfam:PF01477 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA alox12-201 (1) 3595
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM alox12 No data available
    MARKER RELATIONSHIPS
    alox12Contained in: [BAC] DKEY-6N21 (1) (order this)
    alox12Encodes: [EST] fb72a11, IMAGE:7138147 (1) (order this)
    [cDNA] MGC:64120 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199618 (1) 3567bp
    Genomic GenBank:BX005022 (1) 217582bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q7T2A9 (1) 670aa
    Sequence Clusters UniGene:75534 (1)
    Sequence Information (all 12)
    OTHER alox12 GENE PAGES
  • Alliance (1)
  • Gene:322732 (1)
  • VEGA:OTTDARG00000020123 (1)
  • Ensembl(GRCz11):ENSDARG00000069463 (2)
  • ORTHOLOGY for alox12 (Chr: 7)
    CITATIONS (25)