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General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-1421
Gene Name: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Gene Symbol: serpina1
Sequence Ontology ID : SO:0001217

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Previous Names: wu:fb61c07, wu:fb71a09, zgc:153807, zgc:158145

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to the extracellular space. Human  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH serpina1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
alpha 1-antitrypsin deficiency Emphysema due to AAT deficiency 613490
Emphysema-cirrhosis, due to AAT deficiency 613490
Hemorrhagic diathesis due to antithrombin Pittsburgh 613490
chronic obstructive pulmonary disease {Pulmonary disease, chronic obstructive, susceptibility to} 606963
DISEASE ASSOCIATED WITH serpina1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of endopeptidase activity (more)
Cellular Component extracellular space (more)
Molecular Function serine-type endopeptidase inhibitor activity (more)
GO Terms (all 3)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA serpina1-201 (1) 1650
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM serpina1 No data available
MARKER RELATIONSHIPS
serpina1 Contained in: [BAC] CH211-121D13 (order this)
serpina1 Encodes: [EST] fb61c07, fb71a09, IMAGE:6997096
[cDNA] MGC:153807 (1) (order this), MGC:158145 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001077758 (1) 1448 bp
Genomic GenBank:AL845550 (1) 163676 bp
Select Tool
Polypeptide UniProtKB:Q6P5I9 (1) 435 aa
Sequence Clusters UniGene:75688 (1)
Sequence Information (all 29)
ORTHOLOGY for serpina1 ( Chr: 20 )
CITATIONS (26)