Gene

plg

ID
ZDB-GENE-030131-1411
Name
plasminogen
Symbol
plg Nomenclature History
Previous Names
  • wu:fb70e09
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Predicted to be involved in several processes, including blood coagulation; fibrinolysis; and tissue remodeling. Predicted to localize to extracellular region. Is expressed in liver. Human ortholog(s) of this gene implicated in COVID-19; conjunctivitis; myocardial infarction; plasminogen deficiency type I; and thrombophilia. Orthologous to several human genes including PLG (plasminogen).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plg Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
plasminogen deficiency type I Alliance Dysplasminogenemia 217090
plasminogen deficiency type I Alliance Plasminogen deficiency, type I 217090
Associated With plg Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018114 Serine proteases, trypsin family, histidine active site
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Conserved_site IPR018056 Kringle, conserved site
Domain IPR000001 Kringle
Domain IPR001254 Serine proteases, trypsin domain
Domain IPR003609 PAN/Apple domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Family IPR023317 Peptidase S1A, plasmin
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR013806 Kringle-like fold
Homologous_superfamily IPR038178 Kringle superfamily
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Domain Details Per Protein
Protein Length Kringle Kringle, conserved site Kringle-like fold Kringle superfamily PAN/Apple domain Peptidase S1A, chymotrypsin family Peptidase S1A, plasmin Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, histidine active site Serine proteases, trypsin family, serine active site
UniProtKB:Q6PBA6 818
UniProtKB:Q8AVB0 429
UniProtKB:F1Q890 818
UniProtKB:E9QGF2 148
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations