ZFIN ID: ZDB-GENE-030131-139
Gene Name: RAB5A, member RAS oncogene family, a
Gene Symbol: rab5aa    Nomenclature History

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Previous Names: rab5a, fj38g08 (1), hm:zehn1144, wu:fj38g08 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have GTPase activity. Predicted to be involved in several processes, including Rab protein signal transduction; regulation of filopodium assembly; and regulation of long-term neuronal synaptic plasticity. Predicted to localize to axon and postsynaptic early endosome. Is expressed in brain and trunk. Orthologous to human RAB5A (RAB5A, member RAS oncogene family).
Genome Resources: Alliance (1),  Gene:337737 (1),  Ensembl(GRCz11):ENSDARG00000018602 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56009]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17878 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-rab5aa N/A 2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rab5aa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rab5aa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endocytosis (more)
    Cellular Component axon (more)
    Molecular Function GTPase activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rab5aa-201 (1)    Ensembl 2592
    ncRNA rab5aa-002 (1)    Ensembl 691
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM rab5aa No data available
    MARKER RELATIONSHIPS
    rab5aa Contained in: [BAC] CH211-1J13 (1)
    rab5aa Encodes: [EST] fj38g08, zehn1144
    [cDNA] MGC:56009 (1), MGC:77676 (1), MGC:193003 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201485 (1) 2408 nt
    Genomic GenBank:BX950869 (1) 91362 nt
    Select Tool
    Polypeptide UniProtKB:B2GTJ4 (1) 216 aa
    Sequence Information (all 21)
    ORTHOLOGY for rab5aa ( Chr: 19 )
    CITATIONS (34)