Gene

hp

ID
ZDB-GENE-030131-1259
Name
haptoglobin
Symbol
hp Nomenclature History
Previous Names
  • haptoglobin-like (1)
  • HpL (1)
  • hpl
  • wu:fb64e01
Type
protein_coding_gene
Location
Ambiguous Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular space. Is expressed in intestine and liver. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; artery disease (multiple); gout; hyperglycemia; and obesity. Orthologous to several human genes including HP (haptoglobin).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Anhaptoglobinemia] 614081
[Hypohaptoglobinemia] 614081
Associated With hp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001254 Serine proteases, trypsin domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Family IPR008735 Beta-microseminoprotein
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Domain Details Per Protein
Protein Length Beta-microseminoprotein Peptidase S1A, chymotrypsin family Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain
UniProtKB:F8W2Y0 122
UniProtKB:F8W5P2 308
UniProtKB:F8W2X7 153
UniProtKB:A0A2R8RZP1 270
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations