Gene

nqo1

ID
ZDB-GENE-030131-1226
Name
NAD(P)H dehydrogenase, quinone 1
Symbol
nqo1 Nomenclature History
Previous Names
  • wu:fb63c10
  • zgc:77191
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have NAD(P)H dehydrogenase (quinone) activity. Involved in cellular response to xenobiotic stimulus. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in several diseases, including asthma; hematologic cancer (multiple); lung disease (multiple); macular degeneration; and small cell carcinoma. Orthologous to human NQO1 (NAD(P)H quinone dehydrogenase 1).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nqo1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Benzene toxicity, susceptibility to}
{Breast cancer, poor survival after chemotherapy for}
{Leukemia, post-chemotherapy, susceptibility to}
Associated With nqo1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003680 Flavodoxin-like fold
Homologous_superfamily IPR029039 Flavoprotein-like superfamily
Domain Details Per Protein
Protein Length Flavodoxin-like fold Flavoprotein-like superfamily
UniProtKB:E9QEA9 185
UniProtKB:F1QLV5 293
UniProtKB:A0A2R8PW65 289
UniProtKB:Q6P0H2 275
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations