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General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-1187
Gene Name: tryptophan 2,3-dioxygenase a
Gene Symbol: tdo2a
Sequence Ontology ID : SO:0000704

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Previous Names: tdo2, fb62b10, wu:fb62b10

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in protein homotetramerization; tryptophan catabolic process to acetyl-CoA; and tryptophan  ...
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31999 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tdo2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    [?Hypertryptophanemia] 600627
    DISEASE ASSOCIATED WITH tdo2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein homotetramerization (more)
    Molecular Function heme binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004981 (1)
  • InterPro:IPR037217 (1)
  • Pfam:PF03301 (1)
  • EC:1.13.11.11 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA tdo2a-003 (1) 747
    tdo2a-004 (1) 965
    tdo2a-005 (1) 720
    tdo2a-006 (1) 1442
    mRNA tdo2a-201 (1) 1552
    aberrant processed transcript tdo2a-204 (1) 892
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tdo2a No data available
    MARKER RELATIONSHIPS
    tdo2aContained in: [BAC] DKEY-237H12 (1) (order this)
    tdo2aEncodes: [EST] fb62b10
    [cDNA] MGC:171678 (1) (order this), MGC:171685 (1) (order this)
    tdo2aHas Artifact: [cDNA] MGC:103693 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001102616 (1) 1559bp
    Genomic RefSeq:NW_018394922 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A7MBU6 (1) 406aa
    Sequence Clusters UniGene:105118 (1)
    Sequence Information (all 24)
    ORTHOLOGY for tdo2a (Chr: 14)
    CITATIONS (20)