Gene

arfgef1

ID
ZDB-GENE-030131-108
Name
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
Symbol
arfgef1 Nomenclature History
Previous Names
  • hm:zeh1651
  • im:7138204
  • wu:fj64h08
  • zeh1651
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within protein transport and regulation of ARF protein signal transduction. Predicted to be located in Golgi apparatus and perinuclear region of cytoplasm. Is expressed in brain. Orthologous to human ARFGEF1 (ADP ribosylation factor guanine nucleotide exchange factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arfgef1 Human Ortholog
No data available
Associated With arfgef1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000904 Sec7 domain
Domain IPR015403 Sec7, C-terminal
Domain IPR032629 Mon2, dimerisation and cyclophilin-binding domain
Domain IPR032691 Guanine nucleotide exchange factor, N-terminal
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR023394 Sec7, C-terminal domain superfamily
Homologous_superfamily IPR035999 Sec7 domain superfamily
Domain Details Per Protein
Protein Length Armadillo-type fold Guanine nucleotide exchange factor, N-terminal Mon2, dimerisation and cyclophilin-binding domain Sec7, C-terminal Sec7, C-terminal domain superfamily Sec7 domain Sec7 domain superfamily
UniProtKB:A0A2R8Q904 1867
UniProtKB:E7FGL2 1849
UniProtKB:Q6DEJ1 595
UniProtKB:K7DYL1 269
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations