ZFIN ID: ZDB-GENE-030131-108
Gene Name: ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
Gene Symbol: arfgef1    Nomenclature History

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Previous Names: hm:zeh1651, im:7138204, wu:fj64h08, zeh1651

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Orthologous to human ARFGEF1 (ADP ribosylation factor guanine nucleotide exchange factor 1).
Genome Resources: Alliance (1),  Gene:100329953 (1),  Ensembl(GRCz11):ENSDARG00000063474 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7138204]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7145633]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014524Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022883Tg Transgenic Insertion Unknown Unknown DNA
    la022884Tg Transgenic Insertion Unknown Unknown DNA
    sa778 Point Mutation Unknown Premature Stop ENU
    sa10355 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14568 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17540 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30078 Point Mutation Unknown Premature Stop ENU
    sa37862 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH arfgef1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arfgef1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of ARF protein signal transduction (more)
    Molecular Function ARF guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arfgef1-201 (1)    Ensembl 7122
    arfgef1-202 (1)    Ensembl 807
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arfgef1 No data available
    MARKER RELATIONSHIPS
    arfgef1 Contained in: [BAC] DKEY-4M13 (1) (order this)
    arfgef1 Encodes: [EST] fj64h08, IMAGE:7138204 (1), IMAGE:7145633 (1), zeh1651
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009297394 (1)
    Genomic GenBank:CU896568 (1) 225574 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8Q904 (1) 1867 aa
    Sequence Information (all 31)
    ORTHOLOGY for arfgef1 ( Chr: 24 )
    CITATIONS (22)