header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-1060
Gene Name: cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4
Gene Symbol: cyp27a1.4    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: si:dkeyp-68f9.12, wu:fb58e08 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Is expressed in liver. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1).
Genome Resources: Alliance (1),  Gene:322341 (1),  Ensembl(GRCz11):ENSDARG00000055159 (2)
GENE EXPRESSION
All Expression Data: Fig. S2 from Peng et al., 2017
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21547 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34706 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cyp27a1.4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cyp27a1.4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Molecular Function heme binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cyp27a1.4-201 (1)    Ensembl 1819
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp27a1.4 No data available
    MARKER RELATIONSHIPS
    cyp27a1.4 Contained in: [BAC] DKEYP-68F9 (1)
    cyp27a1.4 Encodes: [EST] fb58e08
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001328513 (1)
    Genomic GenBank:BX001051 (1) 213486 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q502F8 (1) 528 aa
    Sequence Clusters UniGene:40298 (1)
    Sequence Information (all 16)
    ORTHOLOGY for cyp27a1.4 ( Chr: 9 )
    CITATIONS (17)