Gene

cyp27a1.4

ID
ZDB-GENE-030131-1060
Name
cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4
Symbol
cyp27a1.4 Nomenclature History
Previous Names
  • si:dkeyp-68f9.12
  • wu:fb58e08 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Is expressed in liver. Orthologous to human CYP27A1 (cytochrome P450 family 27 subfamily A member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Peng et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp27a1.4 Human Ortholog
No data available
Associated With cyp27a1.4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cytochrome P450 Cytochrome P450, conserved site Cytochrome P450, E-class, group I Cytochrome P450 superfamily
UniProtKB:A0A8M3B2U5 314
UniProtKB:F1QAE0 522
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations