ZFIN ID: ZDB-GENE-030131-1033
Gene Name: agrin
Gene Symbol: agrn
Sequence Ontology ID : SO:0000704

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Previous Names: agrin, hm:gc12, sb:eu553, wu:fb57e07

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Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 5 publications
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2005 [eu553]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022570Tg Transgenic Insertion Unknown Unknown DNA
la022571Tg Transgenic Insertion Unknown Unknown DNA
p168 Indel Donor Splice Site of Exon 31 Unknown CRISPR
sa381 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11435 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12413 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15437 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25196 Point Mutation Unknown Premature Stop ENU
    sa29921 Point Mutation Unknown Premature Stop ENU
    sa43979 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43980 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45798 Point Mutation Unknown Splice Site ENU
    Targeting reagents:
    PHENOTYPE
    Data: 13 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH agrn HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    congenital myasthenic syndrome 8 Myasthenic syndrome, congenital, 8, with pre- and postsynaptic defects 615120
    DISEASE ASSOCIATED WITH agrn VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anterior/posterior pattern specification (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000082 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001791 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR002049 (1)
  • InterPro:IPR002350 (1)
  • InterPro:IPR003645 (1)
  • InterPro:IPR003884 (1)
  • InterPro:IPR004850 (1)
  • InterPro:IPR008993 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR036058 (1)
  • InterPro:IPR036364 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01248 (1)
  • PROSITE:PS50024 (1)
  • PROSITE:PS50025 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50027 (1)
  • PROSITE:PS51121 (1)
  • PROSITE:PS51465 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF00053 (1)
  • Pfam:PF00054 (1)
  • Pfam:PF01390 (1)
  • Pfam:PF03146 (1)
  • Pfam:PF07648 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA agrn-001 (1) 8434
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM agrn No data available
    MARKER RELATIONSHIPS
    agrnContained in: [BAC] CH73-233L1 (1) (order this), CH73-313G1 (1) (order this), CH211-135H16 (1) (order this), CH211-203J19 (1) (order this), DKEY-69N13 (1) (order this), DKEYP-73G7 (1)
    [Fosmid] CH1073-121E5 (1) (order this)
    agrnContains: [SNP] rs3729254 (1), rs3729255 (1), rs3729256 (1)
    agrnEncodes: [EST] eu553 (1), fb57e07
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001177452 (1) 6245bp
    Genomic RefSeq:NW_018395149 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:B3GQ72 (1) 2028aa
    Sequence Clusters UniGene:44162 (1)
    Sequence Information (all 63)
    OTHER agrn GENE PAGES
  • Alliance (1)
  • Gene:565373 (1)
  • VEGA:OTTDARG00000030427 (1)
  • Ensembl(GRCz11):ENSDARG00000079388 (2)
  • ORTHOLOGY for agrn (Chr: 23)
    CITATIONS (41)