ZFIN ID: ZDB-GENE-030131-1028
Gene Name: sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
Gene Symbol: sirt2
Sequence Ontology ID : SO:0000704

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Previous Names: wu:fb57d05, zgc:77003

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55966]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019489Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9082 Point Mutation Unknown Premature Stop ENU
    sa13413 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from Zhou et al., 2014
    Observed in:
    DISEASE ASSOCIATED WITH sirt2 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cilium assembly (more)
    Cellular Component centriole (more)
    Molecular Function NAD-dependent histone deacetylase activity (H4-K16 specific) (more)
    GO Terms (all 43)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003000 (1)
  • InterPro:IPR017328 (1)
  • InterPro:IPR026590 (1)
  • InterPro:IPR026591 (1)
  • InterPro:IPR029035 (1)
  • PROSITE:PS50305 (1)
  • Pfam:PF02146 (1)
  • EC:3.5.1.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA sirt2-001 (1) 2589
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sirt2 No data available
    MARKER RELATIONSHIPS
    sirt2Contained in: [Fosmid] CH1073-228B5 (1) (order this)
    sirt2Encodes: [EST] fb57d05
    [cDNA] MGC:55966 (1) (order this), MGC:77003 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199596 (1) 2545bp
    Genomic GenBank:CU693501 (1) 37734bp
    Select Tool
    Polypeptide UniProtKB:F1QE37 (1) 379aa
    Sequence Clusters UniGene:13057 (1)
    Sequence Information (all 23)
    OTHER sirt2 GENE PAGES
  • Alliance (1)
  • Gene:322309 (1)
  • VEGA:OTTDARG00000033429 (1)
  • Ensembl(GRCz11):ENSDARG00000011488 (1)
  • ORTHOLOGY for sirt2 (Chr: 15)
    CITATIONS (28)