Gene

ttk

ID
ZDB-GENE-030123-1
Name
ttk protein kinase
Symbol
ttk Nomenclature History
Previous Names
  • mps1
  • ncp (1)
  • nightcap (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including fin regeneration; meiotic chromosome segregation; and mitotic cell cycle checkpoint. Predicted to localize to kinetochore; nucleus; and spindle. Is expressed in caudal fin and proliferative region. Orthologous to human TTK (TTK protein kinase).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Phenotype Annotation (1994-2006)
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ttk Human Ortholog
No data available
Associated With ttk Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Family IPR027084 Protein kinase Mps1 family
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Domain Details Per Protein
Protein Length Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Protein kinase Mps1 family Serine/threonine-protein kinase, active site Tetratricopeptide-like helical domain superfamily
UniProtKB:F1R3H9 982
UniProtKB:F1R3D0 160
UniProtKB:E9QBU7 983
UniProtKB:Q8AYG3 982
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations