Gene

azin1b

ID
ZDB-GENE-030121-1
Name
antizyme inhibitor 1b
Symbol
azin1b Nomenclature History
Previous Names
  • azin1
  • oazin (1)
  • wu:fj32d12
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have ornithine decarboxylase activator activity and ornithine decarboxylase activity. Predicted to be involved in negative regulation of protein catabolic process; positive regulation of polyamine transmembrane transport; and putrescine biosynthetic process from ornithine. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and liver cirrhosis. Orthologous to human AZIN1 (antizyme inhibitor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With azin1b Human Ortholog
No data available
Associated With azin1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site
Domain IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal
Domain IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal
Family IPR000183 Ornithine/DAP/Arg decarboxylase
Family IPR002433 Ornithine decarboxylase
Family IPR031178 Antizyme inhibitor 1
Homologous_superfamily IPR009006 Alanine racemase/group IV decarboxylase, C-terminal
Homologous_superfamily IPR029066 PLP-binding barrel
Domain Details Per Protein
Protein Length Alanine racemase/group IV decarboxylase, C-terminal Antizyme inhibitor 1 Orn/DAP/Arg decarboxylase 2, conserved site Orn/DAP/Arg decarboxylase 2, C-terminal Orn/DAP/Arg decarboxylase 2, N-terminal Ornithine/DAP/Arg decarboxylase Ornithine decarboxylase PLP-binding barrel
UniProtKB:Q6P6X7 436
UniProtKB:Q8QHL1 419
UniProtKB:F1QHP4 231
UniProtKB:Q801V3 436
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations