Gene

phex

ID
ZDB-GENE-030103-2
Name
phosphate regulating endopeptidase homolog, X-linked
Symbol
phex Nomenclature History
Previous Names
  • wu:fx03e08
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity and metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Is expressed in lapillus. Human ortholog(s) of this gene implicated in X-linked dominant hypophosphatemic rickets. Orthologous to human PHEX (phosphate regulating endopeptidase homolog X-linked).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from 6 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With phex Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked dominant hypophosphatemic rickets Alliance Hypophosphatemic rickets, X-linked dominant 307800
Associated With phex Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR008753 Peptidase M13, N-terminal domain
Domain IPR018497 Peptidase M13, C-terminal domain
Family IPR000718 Peptidase M13
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR042089 Peptidase M13, domain 2
Domain Details Per Protein
Protein Length Metallopeptidase, catalytic domain superfamily Peptidase M13 Peptidase M13, C-terminal domain Peptidase M13, domain 2 Peptidase M13, N-terminal domain
UniProtKB:E9QCT8 285
UniProtKB:F1R6K1 745
UniProtKB:A4QP66 458
UniProtKB:A0A286Y855 727
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations