Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030103-2
Gene Name: phosphate regulating endopeptidase homolog, X-linked
Gene Symbol: phex
Previous Name: wu:fx03e08
Location: Chr: 24   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
  whole organism
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Hypophosphatemic rickets, X-linked dominant 307800
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Molecular Function metalloendopeptidase activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000718 (1)
  • InterPro:IPR008753 (1)
  • InterPro:IPR018497 (1)
  • InterPro:IPR024079 (1)
  • Pfam:PF01431 (1)
  • Pfam:PF05649 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA phex-001 (1) 2640
    phex-002 (1) 912
    ncRNA phex-003 (1) 879
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM phex No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    phex Contained in: [BAC] DKEY-225N3 (1)
    phex Encodes: [EST] fx03e08, IMAGE:7151798
    [cDNA] MGC:162949 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089349 (1) 2666 bp
    Genomic GenBank:BX537285 (1) 150691 bp
    Select Tool
    Polypeptide UniProtKB:F1R6K1 (1) 745 aa
    Sequence Clusters UniGene:25529 (1)
    Sequence Information (all 20)
    OTHER phex GENE PAGES
  • Gene:386969 (1)
  • VEGA:OTTDARG00000021391 (1)
  • Ensembl(Zv9):ENSDARG00000062363 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish phex 24  
    Human PHEX X (Xp22.2-p22.1)
  • OMIM:300550
  • Gene:5251
  • Mouse Phex X ( 72.38 cM)
  • MGI:107489
  • Gene:18675
  • Orthology Details
    CITATIONS (19)