ZFIN ID: ZDB-GENE-021223-2
Gene Name: melanocortin 4 receptor
Gene Symbol: mc4r
Sequence Ontology ID : SO:0000704

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Previous Names: zMC4, si:dkey-151m6.62

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 10 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa122 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa148 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa149 Point Mutation Unknown Premature Stop ENU
    Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH mc4r HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    obesity Obesity, autosomal dominant 601665
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process adenylate cyclase-activating G-protein coupled receptor signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function melanocortin receptor activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000155 (1)
  • InterPro:IPR000276 (1)
  • InterPro:IPR001671 (1)
  • InterPro:IPR001908 (1)
  • InterPro:IPR017452 (1)
  • PROSITE:PS00237 (1)
  • PROSITE:PS50262 (1)
  • Pfam:PF00001 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mc4r-001 (1) 1084
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mc4r No data available
    MARKER RELATIONSHIPS
    mc4rContained in: [BAC] DKEY-151M6 (1) (order this)
    mc4rEncodes: [cDNA] MGC:194184 (1) (order this), MGC:194203 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173278 (1) 981bp
    Genomic GenBank:CR925777 (1) 210659bp Blast at MegaBLAST
    Polypeptide UniProtKB:B0V1P1 (1) 326aa
    Sequence Clusters UniGene:45846 (1)
    Sequence Information (all 18)
    OTHER mc4r GENE PAGES
  • Alliance (1)
  • Gene:286833 (1)
  • VEGA:OTTDARG00000023869 (1)
  • Ensembl(GRCz10):ENSDARG00000015515 (1)
  • ORTHOLOGY for mc4r (Chr: 2)
    CITATIONS (50)