ZFIN ID: ZDB-GENE-021125-1
Gene Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Gene Symbol: smarca5    Nomenclature History

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Previous Names: chunp6878, fb26d12, fb49g04, im:7146484, SWI/SNF related, matrix associated, actin dependent regulator of chromatin A5, wu:fb26d12 (1), wu:fb49g04 (1), zgc:158434

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and DNA-dependent ATPase activity. Involved in cardiac ventricle development and retina development in camera-type eye. Predicted to localize to nucleus. Orthologous to human SMARCA5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5).
Genome Resources: Alliance (1),  Gene:282615 (1),  Ensembl(GRCz11):ENSDARG00000052348 (2)
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7146484]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi550Tg Transgenic Insertion 5' UTR Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11295 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14090 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19604 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32777 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko1049a Small Deletion Unknown Unknown CRISPR
    zko1049b Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-smarca5 1
    MO1-smarca5 N/A 1
    MO2-smarca5 N/A 1
    MO3-smarca5 N/A 1
    DISEASE ASSOCIATED WITH smarca5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH smarca5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardiac ventricle development (more)
    Cellular Component nucleus (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA smarca5-201 (1)    Ensembl 3711
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM smarca5 No data available
    MARKER RELATIONSHIPS
    smarca5 Contained in: [BAC] CH73-251A15 (1), DKEY-76A14 (1) (order this)
    smarca5 Contains: [SNP] rs3727550 (1), rs3727551 (1), rs3727552 (1), rs3727553 (1), rs3727554 (1)
    smarca5 Encodes: [EST] fb26d12, fb49g04, IMAGE:7146484 (1)
    [STS] chunp6878
    [cDNA] MGC:158434 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001081629 (1) 3618 nt
    Genomic GenBank:BX470255 (1) 203708 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B8A552 (1) 1035 aa
    Sequence Information (all 23)
    ORTHOLOGY for smarca5 ( Chr: 1 )
    CITATIONS (44)